Veteran opener David Warner is out of the first Test in Adelaide, but his replacement Will Pukowski is recovering from a concussion after being hit by a bouncer during the tour match.
While current Joe Burns is struggling to score runs, Smith said Australia will find out how well they can handle their batting reserves.
“I think our depth will be tested for Davey out and some new players coming in,” the former captain told reporters.
“It will test us against good Indian attire, no doubt …. they beat us here last time and they are so good.
“No matter who’s there and who’s on the team, hopefully we’ll all do our thing and have a successful summer.”
Pukowski did not travel to Adelaide with the rest of the squad, although he was ruled out of the final pink ball tour, which begins in Sydney on Friday.
Scholars have proposed various ideas about how the 22-year-old could cover Australia if he is not available, including opening third-order batsman Marnus Labuschagne or promoting middle-order batsman Matthew Wade.
Smith, who is rarely comfortable with long waits to bat, said he was free to increase the slot to third.
“It doesn’t bother me much. I bat a little bit in the third, so three or four. If there are fewer than four, I wouldn’t be more happy,” he said. “Anywhere I’m fine.”
The question of whether Smith will regain leadership after Smith’s leadership ban expired in March, two years after the ball tampering scandal in South Africa, has haunted Australian cricket.
Smith has been repeatedly disregarded for leadership roles in this year’s White-Ball series, although coach Justin Langer acknowledged that there were discussions about replacing Aaron Finch when the captain of limited-overs was injured recently.
Wade ended up leading the T20 team and there is still a “process” before Smith can be considered for the role, Langer said.
Smith said he was unaware of the details of that process but “the best thing for the team.”
“Right now I think (Test captain) Tim (Paine) and Finchy are doing really good,” he said. “I’m comfortable with where I am now.”